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Reactivity Documentation

Water and Aqueous Solutions

mixed with

Amides and Imides

Summary

Details

Water and Aqueous Solutions is a reactive group.
Amides and Imides is a reactive group.

Reactivity Predictions (for each pair of reactive groups)

Amides and Imides mixed with
Water and Aqueous Solutions

Hazard Predictions

Hydrolysis of amides can be catalyzed by acids or bases, which would result in the slow generation of ammonia or amines (Loudon, Marc. 2002. Organic Chemistry. 4th ed. New York: Oxford University Press. p. 954-955). Without venting, this process could cause over-pressurization. Caution should be used before proceeding. Further research of comparable examples in the literature or very small scale, carefully controlled experiments may be needed to fully assess compatibility. The generation of gases may be rather slow, however confinement may lead to dangerous conditions.

Caprolactam hydrolysis promotes the polymerization of the substance, however high temperatures are required (> 260 deg. C) (Personal communication with chemical industry experts).

Potential Gas Byproducts