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Hazard Predictions

• Unstable when heated: Reaction products may be unstable above ambient temperatures

Isocyanates can react with 1,3-butadiene to form cyclic amides (2-azetidinone derivatives). These cyclic amides are strained and can be reactive (Russian Chemical Bulletin Volume 18, Number 5, 1016-1019, 1969 - translated from Arbuzov, B. A.; Zobova, N. N.; Yarkova, E. G., Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, No. 5, pp. 1114-1117, 1969).