Reactivity Documentation
Acids, Strong Oxidizing |
mixed with |
Oximes |
Summary
- Generates heat: Exothermic reaction at ambient temperatures (releases heat)
- Toxic: Reaction products may be toxic
Details
Acids, Strong Oxidizing
is a reactive group.
Oximes
is a reactive group.
Reactivity Predictions (for each pair of reactive groups)
Acids, Strong Oxidizing
mixed with
Oximes
Oximes
Hazard Predictions
- Generates heat: Exothermic reaction at ambient temperatures (releases heat)
- Toxic: Reaction products may be toxic
Acids can catalyze the rearrangement of an oxime to an amide, known as the Beckmann rearrangement reaction. This reaction can be exothermic, especially when catalyzed by concentrated acids (Donaruma, L. G.; Heldt, W. Z. (1960). "The Beckmann rearrangement. (Review)". Org. React. 11: 1-156).
Oximes are rapidly hydrolyzed by boiling in dilute acids, a reaction that produces ketones which may be volatile and flammable (George, Frederick; & Saunders, Bernard (1960). Practical Organic Chemistry, 4th Ed. London: Longman. p. 93).