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Reactivity Documentation

Sulfides, Organic

mixed with

Salts, Acidic

Summary

Details

Sulfides, Organic is a reactive group.
Salts, Acidic is a reactive group.

Reactivity Predictions (for each pair of reactive groups)

Sulfides, Organic mixed with
Salts, Acidic

Hazard Predictions

Thioethers and thiols are susceptible to nucleophilic cleavage under acidic conditions; for example, when reacting with an acid that has a nucleophilic conjugate base, such as HI or HBr. These reactions liberate thiols when starting with a thioether, and hydrogen sulfide when starting with a thiol (Loudon, Marc. 2002. Organic Chemistry. 4th ed. New York: Oxford University Press. p. 465-466, 479-480).

These reactions are much more likely to occur with strong acids than weak acids, but a slow reaction with weak acids is not inconceivable. The rate of reaction could be increased by catalytic impurities such as metal salts.

Potential Gas Byproducts