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Reactivity Documentation

Nitriles

mixed with

Acids, Carboxylic

Summary

Details

Nitriles is a reactive group.
Acids, Carboxylic is a reactive group.

Reactivity Predictions (for each pair of reactive groups)

Acids, Carboxylic mixed with
Nitriles

Hazard Predictions

Nitriles can be hydrolyzed to carboxylic acids and ammonium salts by heating them with strong acids (Loudon, Marc. 2002. Organic Chemistry. 4th ed. New York: Oxford University Press. p. 955). This reaction is unlikely to happen with weak acids such as carboxylic acids, but if it does, it is not expected to be hazardous. Further research of comparable examples in the literature or very small scale, carefully controlled experiments may be needed to fully assess compatibility.