365betÓéÀÖ

Reactivity Documentation

Epoxides

mixed with

Oximes

Summary

Details

Epoxides is a reactive group.
Oximes is a reactive group.

Reactivity Predictions (for each pair of reactive groups)

Epoxides mixed with
Oximes

Hazard Predictions

Epoxide rings can be opened with oximes when catalyzed by a base such as an amine or hydroxide. The product is a beta-hydroxy oxime O-ether, which may have biological activity. This reaction can occur at room temperature in some cases (Rad, M. N. S., Behrouz, S., Dianat, M., Synthesis, 2008, No. 13, pp 2055-2064x).