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Hazard Predictions

• Generates heat: Exothermic reaction at ambient temperatures (releases heat)

Carboxylic esters react with amines to form amides and flammable alcohols (Loudon, Marc. 2002. Organic Chemistry. 4th ed. New York: Oxford University Press. p. 967).

Carboxylic esters may react with other nucleophilic weak bases including basic salts to form other carbonyl compounds. These reactions may be exothermic, but the heat generated is not expected to be hazardous (less than 100 cal/gram). Caution should be used before proceeding. Further research of comparable examples in the literature or very small scale, carefully controlled experiments may be needed to fully assess compatibility.