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Reactivity Documentation

Aldehydes

mixed with

Isocyanates and Isothiocyanates

Summary

Details

Aldehydes is a reactive group.
Isocyanates and Isothiocyanates is a reactive group.

Reactivity Predictions (for each pair of reactive groups)

Aldehydes mixed with
Isocyanates and Isothiocyanates

Hazard Predictions

Acetaldehyde reacts violently with isocyanates (Lewis, R.J., Sr. 1992. Sax's Dangerous Properties of Industrial Materials, 8th Edition. New York: Van Nostrand Reinhold. pp. 5).

There is much literature on the condensation reaction between isocyanates and aldehydes, however there is little to support that it will occur at room temperature without catalyst present. Most require strong bases or metallic catalysts and heat to initiate the reaction.