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Reactivity Documentation

Alkynes, with Acetylenic Hydrogen

mixed with

Alcohols and Polyols

Summary

Details

Alkynes, with Acetylenic Hydrogen is a reactive group.
Alcohols and Polyols is a reactive group.

Reactivity Predictions (for each pair of reactive groups)

Alcohols and Polyols mixed with
Alkynes, with Acetylenic Hydrogen

Hazard Predictions

No evidence was found for a hazardous reaction between alcohols and alkynes at ambient conditions. At elevated temperatures and pressures, acetylene can react with alcohols at significantly elevated pressures to create vinyl compounds. For example, 2-methoxypropene was synthesized by the addition of methanol to propyne at temperatures above 120C (Agré, B. A. et al. (1983). Pharmaceutical Chemistry Journal 17 (3): 221).