365betÓéÀÖ

Reactivity Documentation

Alkynes, with No Acetylenic Hydrogen

mixed with

Epoxides

Summary

Details

Epoxides is a reactive group.

Reactivity Predictions (for each pair of reactive groups)

Epoxides mixed with
Alkynes, with No Acetylenic Hydrogen

Hazard Predictions

Alkynes and epoxides can be coupled together by special organometallic catalysts (Miller, K. M., Molinaro, C., and Jamison, T. F. Tetrahedron: Asymmetry 14 (2003) 3619-3625). In the absence of catalysis, this reaction is negligibly slow and is not likely to be hazardous.