Reactivity Documentation
Acetals, Ketals, Hemiacetals, and Hemiketals |
mixed with |
Epoxides |
Summary
- Generates heat: Exothermic reaction at ambient temperatures (releases heat)
Details
Acetals, Ketals, Hemiacetals, and Hemiketals
is a reactive group.
Epoxides
is a reactive group.
Reactivity Predictions (for each pair of reactive groups)
Epoxides
mixed with
Acetals, Ketals, Hemiacetals, and Hemiketals
Acetals, Ketals, Hemiacetals, and Hemiketals
Hazard Predictions
- Generates heat: Exothermic reaction at ambient temperatures (releases heat)
Epoxides are known to react with alcohols, as shown in the following examples. Acetals have alcohol-like structures, and are likely to react in a similar way to alcohols.
Reaction of glycerol and ethylene oxide is exothermic, and can accelerate to explosion (Anon. 1979. Loss Prevention Bulletin (028):92-93).
Ethylene oxide has an undefined incompatibility with alcohols (Lewis, R.J., Sr. 1992. Sax's Dangerous Properties of Industrial Materials, 8th Edition. New York: Van Nostrand Reinhold. pp. 1611).
Reaction between epoxides and alcohols require acid catalysts to occur at any appreciable rate (T. W. G. Solomons, C. B. Fryhle., Solomons & Fryhle's Organic Chemistry. 8th ed.; John Wiley & Sons, Inc., New York, 2004).